Investigators with the Human Tumor Atlas Network (HTAN) published a collection of research studies, methods, and data related to the exploration of tumor evolution in space and time. https://lnkd.in/eTu97zEY
NCI Division of Cancer Biology
Government Administration
Rockville, Maryland 6,381 followers
Supporting fundamental cancer research that lays the foundation for advances in cancer prevention, diagnosis & treatment
About us
The Division of Cancer Biology (DCB) of the National Cancer Institute (NCI) supports basic research in all areas of cancer biology, from structural insights to mechanisms of metastasis. These fundamental studies provide the building blocks to new cancer prevention and diagnostic strategies, clinical trials, and anti-cancer treatments. NCI Privacy Policy: https://www.cancer.gov/policies/privacy-security
- Website
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https://www.cancer.gov/about-nci/organization/dcb
External link for NCI Division of Cancer Biology
- Industry
- Government Administration
- Company size
- 501-1,000 employees
- Headquarters
- Rockville, Maryland
Updates
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In a National Cancer Institute (NCI) funded study, Sharanya Sivanand, Matthew Vander Heiden MD, PhD, et al. found that cancer tissue of origin influences the growth and metabolism of metastases. The findings may explain why cancers tend to metastasize more frequently to certain tissues and organs. https://lnkd.in/eNjGy3bi
Cancer tissue of origin constrains the growth and metabolism of metastases - Nature Metabolism
nature.com
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REGISTER TODAY! Join us at a National Cancer Institute (NCI) Think on Dec. 9 – 10, 2024 on Studying the Context and Complexity of Oncogenes and Oncogene Addiction Paradigms in MalignanciEs (SCOPE). The meeting will bring together a group of thought leaders in the field of oncogene biology for stimulating discussions on key questions and challenges in this research area. It is designed around topics/sessions that can promote novel thinking and potentially highlight new approaches towards understanding the functions of oncogenes in precancers and early cancers, as well as oncogene addiction during tumor evolution. Additional information, including the registration form to virtually attend the think tank, can be found at https://lnkd.in/eWt4AeZu.
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Our division’s research portfolio supports a broad range of investigator-initiated research in its mission to facilitate existing and emerging research areas in basic #CancerBiology. https://lnkd.in/ehUBPB9e
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#CancerBiology researchers are advancing the mechanistic understanding of cancer and informing the development of new cancer prevention, early detection, and treatment strategies. Some examples include: ◾ Sita Kugel is investigating the biology of pancreatic cancer and cholangiocarcinoma. ◾ DeNardo David is examining how the tumor microenvironment affects immune responses to cancer. ◾ Dr. Kate Chiappinelli studies the epigenetic regulation of immune signaling in cancer. ◾ Dr. Erika Moore is engineering biomaterial models to advance biomedical research and address health disparities. https://lnkd.in/eG_kYDrf
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Did you know that you can subscribe to our division's Cancer Biology Bytes email to learn about recent fundamental #CancerResearch discoveries? https://lnkd.in/exaSEDp3
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In a study funded by our division, Sreya Bagchi, Edgar Engleman, et al. found that increased tumor acidity suppresses inflammatory responses of tumor associated macrophages through GPR65 (an acid-sensing receptor) to drive obesity associated cancer growth in preclinical models. https://lnkd.in/egwAQfAh
The acid-sensing receptor GPR65 on tumor macrophages drives tumor growth in obesity
science.org
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On Nov. 19 & 22 from 7:00 - 7:30 pm ET, we will be hosting a Pancreatic Cancer Awareness Month Twitter/X Chat (#PCAMChat24) at @NCICancerBio. Join Edna (Eti) Cukierman, Kathy DelGiorno, Christopher Halbrook, Ashley Kiemen, Anirban Maitra, Kenneth Olive, Tobiloba Oni, Mara Sherman, and Nina Steele to discuss advances and opportunities in #PancreaticCancer research!
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Did you know that our division provides information and guidance about the National Institutes of Health Data Management and Sharing Policy for researchers? https://lnkd.in/eFZ3RqUN
DCB Guidance for the NIH DMS Policy
cancer.gov
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Over the past year, research projects funded by our division have led to new discoveries and advances in fundamental #CancerResearch. https://lnkd.in/evSJQ6g9 #NCICancerBioProgress
Research Advances in Cancer Biology
cancer.gov