European Bioinformatics Institute | EMBL-EBI

Congratulations to the researchers involved in creating the first comprehensive spatial atlas of the developing human thymus! Part of the Human Cell Atlas, this study published in Nature, provides insights into how immune responses are built and maintained from early life. This research could inform immune therapies, including the potential to engineer artificial thymus organs for patients with compromised immune systems. Find out more and learn how former Wellcome Sanger Institute and EMBL-EBI Postdoctoral Fellow, nadav yayon, helped to develop a new standardised high resolution spatial mapping method to study the various stages of thymus development. https://lnkd.in/erpfW6HH #immunology #HumanCellAtlas 

Thank you to leading scientists around the world for signing the GBC’s Open Letter calling for support to sustain global biodata resources. If you haven’t already signed the letter, please do so. Click the link https://bit.ly/3UT0c6n

Meet Dan Trigg, our new Head of Campus Operations. He leads some of the teams that ensure our institute runs smoothly, from preparing our new Thornton Building for its first occupants, to making sure everyone understands the importance of health and safety. https://lnkd.in/eQk2qb3q #bioinformatics #collaboration

The Global Alliance for Genomics and Health Plenary in Melbourne provided a rare opportunity for us to bring together a global group of infrastructure experts working at the forefront of human genomics data sharing and management. Read more about the fruitful discussions in our latest news 👉 https://lnkd.in/g2dYPx7b Thanks to everyone who joined the meeting including representatives from Australian Genomics, Broad Institute of MIT and Harvard, CanDIG, ELIXIR, European Bioinformatics Institute | EMBL-EBI, Genomic Data Infrastructure (GDI), GA4GH, CSC - IT Center for Science, McGill University, Murdoch Children's Research Institute (MCRI), National Computational Infrastructure, Ontario Institute for Cancer Research, University Health Network, and University of Melbourne Centre for Cancer Research

Climate change is accelerating the decline of global biodiversity, leading to the loss of species and increased prevalence of diseases. Researchers worldwide are trying to find solutions for these challenges but to do this, they need vast amounts of data and robust analysis tools. At EMBL-EBI we are supporting global biodiversity research by: 🌱 Making biological data openly available to the scientific community 🌐 Collaborating on global biodiversity initiatives such as the Earth BioGenome Project, Tara Ocean expeditions, BlueRemediomics and more  👩💻 Providing bioinformatics training and resources to support researchers worldwide Find out more about our ongoing projects, meet our experts, and access bioinformatics training on our new dedicated biodiversity landing page 👇 https://lnkd.in/e3_VkV4H #biodiversity #climate #bioinformatics 

Determining a protein's 3D structure is fundamental to understanding its functions. This information advances research in biology, medicine, and drug design. A new study, published in the journal Scientific Data, introduces a novel AI-human hybrid workflow that accelerates protein research. By combining expert curation with AI models, researchers at the Protein Data Bank in Europe (PDBe) and Europe PMC have developed a system that rapidly identifies key terms related to protein structures in scientific literature. The insights gained from this AI-human process can provide information to support drug target validation and propel the development of novel treatments. Explore this blog post to find out more. https://lnkd.in/ei-dSxHx #ai #proteinresearch #machinelearning

Our data resources enable scientists to study evolutionary processes, ecosystem health and to gain insights to help inform conservation strategies. 🧬 Tools like the Biodiversity Portal and Ensembl Rapid Release provide quick access to new genome sequences. 🦠 MGnify offers insights into microbial communities and their role in ecosystem function. 💻 UniProt and Protein Data Bank in Europe (PDBe) allow scientists to explore the structure and function of proteins across species. Many of our resources also support projects like the Earth BioGenome Project and Darwin Tree of Life to help drive global biodiversity research 🌍 Learn more and find useful tools for your own biodiversity research. https://lnkd.in/ehZtjVqk #biodiversity #climatechange #opendata #alphafold EMBL European Nucleotide Archive

Exciting times ahead as the BioChemGraph project launches its first dataset🚀 This collaboration between the Protein Data Bank in Europe (PDBe), ChEMBL and CCDC - The Cambridge Crystallographic Data Centre is set to support drug discovery by integrating crucial structural and bioactivity data. Looking forward to seeing how this open-access resource empowers researchers worldwide! #structuralbiology #chemicalbiology #drugdiscovery