BRIC-National Institute of Immunology’s Post

Inflammatory changes can be found in the bone marrow of a whole range of hematological malignancies 🔥 But why are the downstream effects so different? Tom Cupedo and I explore this question in our new review out in Nature Reviews Immunology, with brilliant help of Lanpeng Chen and Marc Raaijmakers sharing their expertise in MDS/AML We hope you enjoy! https://rdcu.be/dBkF2

Clinical research in Immunology is accelerating at pace. There is often a high unmet need in diseases such as Cutaneous Lupus Erythematosus (CLE) and Idiopathic Inflammatory Myopathies (IIM), this clinical development can’t come soon enough.   At AstraZeneca, we’re innovating to deliver targeted care options that tackle the underlying drivers of immune-mediated disease.   Our ambition is to transform care for immune-mediated diseases by moving beyond symptom control to achieve disease modification, remission and, one day, cure. Learn more about our immunology ambition https://bit.ly/3ZAzClX.

Despite clear evidence, chronic Lyme disease remains controversial. In our upcoming webinar on June 13th, Dr. Embers, an Associate Professor in the Division of Immunology and the Director of Vector-borne Disease Research at the Tulane National Primate Research Center, will discuss why Lyme persists and how her recent research may help to address it. More about the research: Dr. Embers and a team of researchers from Tulane University have found that a combination of antibiotics is more effective in treating Lyme disease than the commonly prescribed course of one single antibiotic. Their results could pave the way for improved Lyme disease treatments, particularly in persistent cases that have not responded to standard treatment with a single antibiotic. Learn more or sign up now for this free event: https://lnkd.in/e2JMVSab #projectlyme #lyme #lymediseaseawareness #coinfections #tickbornediseases #chroniclyme #fightlyme #event #webinar #lymediseaseawarenessmonth

Is FcyR activity convoluting your immunology study? Find better answers using fewer resources with FcResolv® hIL-15 NOG mice where these FcγRs are absent. Learn More: https://bit.ly/4cRyoXd

Check out my publication on Exosome in Fish and Shellfish Immunology "Isolation and characterization of plasma-derived exosomes from olive f lounder (Paralichthys olivaceus) and their wound healing and regeneration activities" https://lnkd.in/gY-nChEe

Check out our latest review on the Vγ9Vδ2 TCR mode of sensing PAg for detailed and updated info!! https://lnkd.in/eMGmJkb3 Thomas Herrmann, Wiley and European Journal of Immunology

Check out my publication in Fish and Shellfish Immunology. Octominin: An antibacterial and anti-biofilm peptide for controlling the multidrug resistance and pathogenic Streptococcus parauberis https://lnkd.in/g6au_MY3

I’m incredibly proud of the work we’re doing at AstraZeneca to unlock the drivers of immune mediated diseases with high unmet need, such as cutaneous lupus erythematosus (CLE) and idiopathic inflammatory myopathies (IIM).   These complex conditions are challenging to diagnose and treat, leaving patients with limited care options. But with our growing presence in Immunology, we’re working to improve outcomes for people living with these conditions, by following the science that go beyond just symptom management. Learn more on how we’re advancing the science in immune mediated diseases: https://bit.ly/3ZAzClX.

Monica Embers, PhD, is Associate Professor of Microbiology and Immunology at the Tulane National Primate Research Center. Her passion for researching and curing Lyme disease has changed the lives of so many patients. Learn more about Dr. Embers in this episode of #TulaneMedInsider

What’s the role of Immunology in the neuroendocrine system? Let’s talk about it!