Members of our executive team will participate in a fireside chat at the Jefferies London Healthcare Conference next week. Tune in to hear how we’re using our Bicycle® technology platform to develop potential therapies for #cancer, and our milestones ahead. https://bit.ly/3O5dzg5
Bicycle Therapeutics
Biotechnology Research
Cambridge, England 36,632 followers
Precision-Guided Therapeutics
About us
Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company that is harnessing the power of bicyclic peptides and leveraging Nobel Prize-winning science to develop a new and differentiated class of medicines to treat cancer and other diseases. Bicycle® molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin, previously BT8009, a Bicycle® Toxin Conjugate (BTC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radio Conjugates (BRC™) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology. Bicycle is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA.
- Website
-
https://www.bicycletherapeutics.com
External link for Bicycle Therapeutics
- Industry
- Biotechnology Research
- Company size
- 201-500 employees
- Headquarters
- Cambridge, England
- Type
- Public Company
- Founded
- 2009
- Specialties
- Drug Discovery, Phage Display, Peptide Therapeutics, and Biotechnology
Locations
-
Primary
Get directions
Granta Park
Cambridge, England CB21 6GP, GB
-
Get directions
35 Cambridgepark Dr
Cambridge, Massachusetts 02140, US
Employees at Bicycle Therapeutics
Updates
-
A warm welcome to the new hires who joined #TeamBicycle in October. We are happy to have you join our Development, Finance and Research teams! Learn more about our careers and culture: https://bit.ly/3TS7ZA8.
-
-
We recently held our Second Annual Macmillan Coffee Morning in support of Macmillan Cancer Support, one of the UK’s leading #cancer charities. Our team baked a slew of sweet treats for colleagues to enjoy with their coffee and tea, raising a total of £1,400 to help provide practical, emotional and financial support to those living with cancer.
-
-
A big congrats to our #TeamBicycle colleague Mike Hannay on his appointment to the BioIndustry Association (BIA) Board of Directors! 👏 We are proud to have him work alongside UK #biotech leaders to advance initiatives and foster an ecosystem that enable companies to grow and deliver world-changing #innovation. https://lnkd.in/e4mss7iK
🌐 Exciting times ahead as we welcome our new Board representatives, who will steer the ship for the next three years. Their expertise and passion will undoubtedly contribute to the continued growth and success of the association 👏 🤝 Join us in welcoming: Newly elected Board of Directors: ⭐ Mike Hannay, Chief Product and Supply Chain Officer, Bicycle Therapeutics ⭐ Simon Kerry, Chief Executive Officer, Curve Therapeutics ⭐ Sarah Korman, General Counsel and Head of Legal and Business Operations, Isomorphic Labs ⭐ Chris Williams, Chief Business Officer, Autolus Therapeutics Re-elected Board of Directors : ⭐ Lisa LM Anson, Chief Executive Officer, Redx Pharma ⭐ Peter Finan, Partner, Epidarex Capital Find out more ➡️ https://lnkd.in/e4mss7iK #BIABoard #NewLeadership #BoardElections
-
Today we reported recent business progress and third quarter 2024 financial results. Read our press release here: https://bit.ly/3YvOr6S.
-
-
October marks Black History Month in the UK and Ireland. For our #TeamBicycle colleague Yasmin Kinobe MPH, the month provides an opportunity to reflect and reconnect with her family’s roots on the African continent. "My mother first stepped foot in the UK in her twenties with a scholarship to London School of Economics to study her master’s degree, and yet the odds were stacked against her as she came from humble beginnings. Having lost her mother at 3 years old and been brought up by extended relatives, it is in the UK she met my father in the 1980s who was also Ugandan but working and living in Nigeria as an expat. The rest was history as they married and had me and my sisters soon after. She maintained a career in social work for 30+ years and continues to give back to her community, opening a transit home for children in Uganda. "Growing up as Black British in London has been a rich experience, being surrounded by a melting pot of nationalities regardless of race. Within the Black community alone, we represent numerous countries from Africa and the Caribbean and have made great contributions to the Commonwealth. "This year, the theme of Black History Month is 'Reclaiming Narratives,' highlighting the part played by the Black community in British life and bringing untold histories to the forefront. Children across the nation are being educated on the Windrush generation of emigrants from Jamaica who were brought to the UK in the 1940s, and Mary Seacole who rivalled Florence Nightingale in her assistance to wounded military personnel during the Crimean war. These were things I was never taught in school, so the efforts made to recognise and build pride as well as awareness are truly admirable."
-
-
Today we announced first human imaging data for our Bicycle Radionuclide Conjugate® targeting MT1-MMP, a novel tumor antigen, and outlined our strategy to develop next-generation #radiopharmaceuticals. Read more here: https://bit.ly/3UlNAoe.
-
-
At #EANM24, we look forward to sharing preclinical and first human imaging data for our Bicycle® Radio Conjugate targeting MT1-MMP, a novel tumor antigen expressed in many types of #cancer. We’ll also host a webcast for investors to review the data and outline our #radiopharmaceuticals strategy. More info: https://bit.ly/3NsDrlJ.
-
-
A warm welcome to our #TeamBicycle September new hires who joined our Development, Commercial, Finance, Clinical, Regulatory, Research and CMC & Supply Chain teams! Learn more about our careers and culture: https://bit.ly/3TS7ZA8.
-
-
Congrats to our #TeamBicycle colleague Zafar Qadir on his promotion to Chief Legal Officer and General Counsel! Zaf has played a critical role in supporting our company’s growth, and we look forward to seeing him succeed in this elevated role.
-