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Does "update_blastdb.pl" support the Accession-Based BLAST databases?

Yes. The update_blastdb.pl program is a part of the BLAST+ command line suite of applications and can conveniently download the BLAST databases.  We have updated the version that accompanies the BLAST+ 2.8.1 executables (January 2019) to support  Accession-Based BLAST databases. There is a new parameter for update_blastdb.pl called -blastdb_version which allows you to set the version of the databases to which you wish to update.

 

Example:  

 

$ update_blastdb.pl nr -decompress -blastdb_version 5