ARTIKEL - April 2014, Vol.10, No.04
Pengaruh pemberian pangan antioksidan terhadap kadar malondialdehid plasma mahasiswi penyuka gorengan
Inti Makaryani*, Leily Amalia*, Novi Rizqi Ramadhani, Karina Indah Pertiwi, Desy Dwi Aprillia
Background : Antioxidant elements such as vitamin C, vitamin E, lycopene, chlorophyl, polifenol, and other fl avonoid existed on various foods of fruits, vegetable, tea, coffee, and others. The foods are usually consumed in our every single day. Some previous studies had shown that there were various benefi ts of antioxidant elements for animal and human health. However, the antioxidative effect of the antioxidant elements in combating free radicals in the body are not similar for each other
Objective : This study was aimed to analyze the effect of antioxidant foods (green grass jelly drinks, tomato juice, papaya, and black tea) on blood levels of malondialdehyde (MDA) among college students.
Method : The study was designed by pre-post test control study. Subjects were divided into fi ve groups, consisted of four intervention groups and one control group. Every group consisted 6 persons. Each subject was asked to consume one kind of antioxidant foods in a single serving size per day for 21 days.
Result : All of the subjects who consumed fried foods had high MDA levels in pre-intervention. The results of this study showed that MDA level in the group of green grass jelly drink decreased signifi cantly (p<0.05). Plasma MDA levels tend to decline between pre and post intervention in the group of tomato juice, papaya, and tea, but they were not statisticaly signifi cant (p>0,05).
Conclusion : The antioxidant foods which can reduce plasma MDA level were green grass jelly drink. However, tomato juice, papaya and tea can also reduce plasma MDA level, but not statistically signifi cant.
Key words : plasma MDA level, antioxidant source food, intervention, fried foods
1 Korespondensi : Departemen Gizi Masyarakat, Fakultas Ekologi Manusia (FEMA), Institut Pertanian Bogor, Bogor 16680, e-mail:
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Kejadian malaria dan status gizi balita di Kabupaten Manokwari Provinsi Papua Barat
Background : The prevalences of severe acute malnutrition, moderate acute malnutrition and low birth weight (LBW) in West Papua Province is higher than the national prevalence. Malaria disease especially in infant, is also of concern in this province. Manokwari District is regarded as malaria endemic area due to the high morbidity rate in the entire district.
Objective : To determine the incidence of malaria, nutritional status of children and to analyze the relationship between two of them.
Method : The methodology that used in this research is cross-sectional design conducted in four health centers in Manokwari with a sample of 100 children aged two to fi ve years. The data were analized using Chi-Square analysis and logistic regression analysis.
Result : The incidence rate of malaria in Manokwari district is high. This is because the number of infant that was infected highly and lowly by malaria do not vary much. Results shows that 42% children suffering from severe malaria, particularly tropical malaria type, with a frequency of more than two times in six months so that it had direct effect on appetite and weight. Average nutritional status based on weight/height and height/age is normal while according to weight/age is not normal. Infants with severe and moderate acute malnutrition are not found in this study.
Conclusion : The incidence rate of malaria in children under fi ve in the district of Manokwari is high, the nutritional status of children under fi ve in the past are in the normal category and at the time of the study were not normal, this is due at the time of the study many infants experience pain and therefore contributes to the appetite that directly affect body weight of infants. Furthermore, it is known that there is a relationship between the incidence of malaria by the nutritional status of children in the district of Manokwari.
Key words : malaria, nutritional status, children, malnutrition, Manokwari, West Papua
1 Korespondensi : Jurusan Sosial Ekonomi Pertanian, Fakultas Pertanian, Universitas Negeri Papua, Jl. Cenderawasih No. C.83 Amban Manokwari, e-mail:
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Pemberian jahe instan terhadap kejadian mual muntah dan asupan energi pada ibu hamil trimester pertama
Nurfalah Setyawati1, Mae Sri Hartati Wahyuningsih2, Detty Siti Nurdiati3
Background : Pregnancy causes increased energy metabolism, therefore needs of energy and other nutrients increase during pregnancy. Lack of energy and nutrients could adversely affect the mother and fetus. Nausea and vomiting is a common problem in the fi rst trimester of pregnancy. If not treated the mother and fetus can be at risk of malnutrition due to lack of energy intake. Traditional treatment is an option that is considered safe. Ginger has been used to treat a variety of medical problems including nausea and vomiting. Ginger works in the digestive tract by increasing the gastric and intestinal motility.
Objective : This study aimed to determine the effectiveness of instant ginger containing 290 mg ginger juice, to reduced the incidence of nausea and vomiting of pregnancy and increased maternal energy intake during the 24 hours.
Method : The study design is experimental, pre-post control group, involving 101 pregnant women with gestational age less than 15 weeks in RSB Sayang Ibu, puskesmas Klandasan Ilir and Sepinggan in Balikpapan. Research subjects were drawn at random and given the instant ginger or placebo, 2 times a day for a week. All of the subjects were assessed on the level of nausea, vomiting and a 24-hour energy intake during pre and post intervention. The use of drugs or supplementation from the doctor/midwife were recorded and not be stopped.
Result : The rate of nausea and vomiting decreased signifi cantly in the ginger group (52%) compared to placebo (17.7%) (p<0.05). Instant ginger may reduce nausea and vomiting rate 6 times higher than placebo (p<0.05). The average amount of energy intake (calories) for 24 hours increased signifi cantly in the ginger group (1629.58 kcal + 468.04 kcal; p<0.05) compared to placebo (1160.27 kcal + 341.85 kcal; p>0.05). Instant ginger may increase the average amount of energy intake 24.5 times higher than placebo (p<0.05).
Conclusion : Instant ginger effective to reduce nausea and vomiting of pregnancy and increase the amount of energy intake (calories) in pregnant women who experience nausea and vomiting of pregnancy.
Key words : ginger, nausea and vomiting of pregnancy, energy intake
1 Korespondensi : Jl. Indrakila No.107 RT 04, Kel. Gunung Samarinda Baru, Balikpapan, Kalimantan Timur, 76125, e-mail:
2 Departemen Farmakologi dan Terapi Fakultas Kedokteran Universitas Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55281
3 Departemen Obstetri dan Ginekologi Fakultas Kedokteran Universitas Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55281
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Pola makan suku asli Papua dan non-Papua sebagai faktor risiko kejadian hipertensi
Sarni Rante Allo Bela1, Bambang Djarwoto2, I Made Alit Gunawan3
Background : Hypertension is one of the problems in the medical and public health sector. The prevalence of hypertension in Jayapura City is 23,8%. Hypertensive disease was ranked 6th among the top 10 diseases in Abepura Hospital. The risk factors, diet containing high fat, high sodium, low potassium and excessive alcohol consumption has contributed to the increasing of blood pressure.
Objective : To determine the degree of hypertension difference between Papuans and non-Papuans, and the effect of asupan of fat, sodium, potassium and alcohol consumption as risk factors for hypertension in each tribes.
Method : The study was an observational analytic with a case control design. Samples are 248 which is divided in 62 cases and 62 controls on each tribe. Data analysis using statistical independent t-test, Chi-Square, Maentel Haenzel, Multiple Regression Logistic.
Result : Non- Papuan tribes had 1.9 times higher risk of hypertension stage 2. Fat intake of indigenous Papuans (OR=3.250) and non-Papuans (OR=3.275) correlated signifi cantly. Sodium intake signifi cantly associated in indigenous Papuans, but the non-Papuans, have a signifi cant relation (OR=2.531). There was a correlation between potassium intake in indigenous Papuans (OR=2.348), but the non-Papuans, was not. Consumption of alcohol in indigenous Papuans was signifi cantly associated (OR=2.343), but the non- Papuans, was not. Multivariate analysis showed that psychosocial stress, consumption of alcohol, family history of hypertension, and potassium intake were contributing in indigenous Papuans. Intake of fat, sodium asupan, and obesitas were contribute in non-Papuan tribes.
Conclusion : Non-Papuan tribes prone to has hypertension stage 2. In Papuans, fat intake (> 30%), potassium intake (<2000 mg) and excessive alcohol (> 2 glasses/day) are risk factors. In the non-Papuan, fat intake (> 30%) and sodium intake (> 2300 mg) are risk factors for hypertension.
Key words : hypertension, fat intake, sodium intake, potassium intake, alcohol consumption, indigenous Papuan and non- Papuans
1 Korespondensi : Gg. Jati VI / 9 A Perumnas II Waena, Jayapura, Papua, e-mail:
2 Sub Bagian Ginjal dan Hipertensi Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Gadjah Mada / Rumah Sakit Umum Pusat Dr. Sardjito, Jl. Farmako, Sekip Utara, Yogyakarta 55281
3 Jurusan Gizi, Politeknik Kesehatan Kementerian Kesehatan Yogyakarta, Jl. Tata Bumi No. 3 Banyuraden Gamping, Sleman, Yogyakarta
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Efek pemberian ekstrak teh hijau (Camellia sinesis (L) O. Kuntze) var. Assamica terhadap total lemak tubuh dan profi l lipid wanita dewasa overweight dan obesitas
Ernawati Hardani1, Wiryatun Lestariana2, Susetyowati3
Background : Overweight and obesity can cause high body fat total and lipid profi le in the blood that bring risk for diseases to the bearer. Some studies on green tea extract supplementation have been undertaken to fi nd out its effect to fat reduction in children, men, and mice and the result showed reduction in body fat, weight, appetite, and triglyceride level. This study uses green tea extract supplemented to overweight and obese women.
Objective : To fi nd out the reduction of body fat total and lipid profi le (total cholesterol, triglyceride, LDL, HDL) in the blood of overweight and obese women personnel of Yogyakarta Municipal Health Offi ce supplemented with green tea extract.
Method : The study was randomized double blinded control trial. Subject of the study were overweight and obese women of 35- 55 years old personnel of Yogyakarta Municipal Health Offi ce. Samples were 86 women randomly taken, comprising experiment group and control group, each of which consisting of 43 women. Each group had diet according to individual appetite. Both groups were given capsules of similar form and color but different ingredients: placebo and green tea extract. The experiment took three months. Blood was taken before and after the experiment to identify lipid profi le (total cholesterol, triglyceride, LDL, HDL). Body fat total was examined using body fat analyzer. Data analysis used paired t-test.
Result : Green tea extract supplementation could signifi cantly reduce body fat total and insignifi cantly reduce cholesterol level, triglyceride and LDL, signifi cantly increase HDL in overweight and obese women.
Conclusion : Green tea extract supplementation could reduce body fat total and increase HDL (p<0.005).
Key words : overweight women, obese women, green tea extract, body fat total, lipid profi le, LDL, HDL, triglyceride, cholesterol
1 Korespondensi : Dinas Kesehatan Kota Yogyakarta (Puskesmas Jetis Kota Yogyakarta), Jl. Diponegoro 91, Yogyakarta, e-mail:
2 Bagian Biokimia, Fakultas Kedokteran Universitas Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55281
3 Program Studi Gizi Kesehatan, Fakultas Kedokteran Universitas Gadjah Mada, Jl. Farmako, Sekip Utara, Yogyakarta 55281
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Faktor risiko dan asupan isofl avon pada pasien kanker payudara
I Wayan Dwija Karyasa1, Johan Kurnianda2, Herni Astuti3
Background : Breast cancer is non communicable chronic disease the prevalence of which is increasing all over the world, including in Indonesia and particularly East Java. Causes of breast cancer are unknown. Some studies show risk factors of breast cancer are hormonal, genetic, reproductive and endocrinologic factors. There is isofl avon compound in soybeans that is known as anti cancer with anti estrogen activities.
Objective : The study was aimed at identifying risk factor and the difference of isofl avon intake between breast cancer patients and healthy people in hospitals.
Method : The study was analytic observational using matched case control study design at comparison 1:2 with matching on status of menopause. Cases were positive receptor estrogen breast cancer patients newly diagnosed during the fi rst visit at hospital outpatient Oncologic Surgery Polyclinic. Controls were staff considered healthy based on the result of health examination at Dr. Ramelan Naval Hospital of Surabaya. Cases comprised 49 people and controls 98 people taken through consecutive method. Data consisted of identity of samples, weight, height, isofl avon intake, family history, use of hormon replacement therapy and parity. Intake of isofl avon was obtained from semiquantitative food frequency questionnaire (SQ-FFQ) and statistical test used Chi-Square and Odd Ratio (OR).
Result : There was difference in isofl avon intake and family history between cases and controls (p<0.05) and there was association between isofl avon intake (OR=2.58; p=0.007) and family history (OR=18; p=0.002) and the incidence of breast cancer. There was no association between status of obesity, parity, and use of hormon replacement therapy
Conclusion : There are differences in isofl avone intake of breast cancer patients compared with healthy people and there was no difference in the status of obese breast cancer patients compared to healthy individuals and isofl avone intake less 2.85 times the risk of breast cancer compared with adequate intake of isofl avones.
Key words : risk factors, isofl avon intake, breast cancer
1 Korespondensi : Rumah Sakit Angkatan Laut Dr. Ramelan Surabaya, Jl. Gadung No. 1 Surabaya, Jawa Timur, e-mail:
2 Instalasi Kanker Terpadu Rumah Sakit Umum Pusat Dr.Sardjito, Jl. Kesehatan No. 1, Yogyakarta 55281
3 Instalasi Gizi Rumah Sakit Umum Pusat Dr. Sardjito, Jl. Kesehatan No. 1, Yogyakarta 55281
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